Free interactive chemistry · SIM-ORG-E2-001
E2 anti-periplanar elimination
E2 elimination: a base pulls off an H while the leaving group departs, all in one step.
Open the interactive simulation →How to use this simulation
- Play the mechanism and follow the three curved arrows.
- Rotate the 3D view to see the H and the leaving group on opposite sides (anti-periplanar).
- Check the rate law in “Facts”.
What to notice
- One step: rate = k[substrate][base].
- The H and the leaving group must be anti to each other.
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Why does a strong, bulky base favour E2?
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